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Biociphering Advisory Board
William Goddard, Ph.D.
Charles and Mary Ferkel Professor of Chemistry, Materials Science, and Applied Physics, CalTech
Co-Founder, ALLOZYNE
Dr. Goddard received his B.S. degree with Highest Honors from the University of California, Los Angeles, and his Ph.D. in Engineering Science from the California Institute of Technology (CalTech). Since 1978, Dr. Goddard has had a distinguished career at CalTech, with appointments to the position of Professor of Chemistry and Applied Physics and Professor of Theoretical Chemistry. He has been Director of both the National Science Foundation (NSF) Materials Research Group and the NSF Grand Challenge Application Group at CalTech. Since 1990, Dr. Goddard has served as Director of Materials and Process Simulation Center (MSC) at Caltech and, since 2001 he has been the Charles and Mary Ferkel Professor of Chemistry, Materials Science and Applied Physics. Over the span of his career, Dr. Goddard has authored more than 735 research publications.
Dr. Goddard has received numerous awards and honors, including: the American Chemical Society Award for Computers in Chemistry (1988), the Feynman Prize for Nanotechnology Theory (1999), the American Chemical Society Award for Theoretical Chemistry (2007) and the NASA Space Sciences Award (2000 and 2007).
Leroy Hood, M.D., Ph.D.
President & Co-Founder, Institute for Systems Biology
Dr. Hood is co-founder and President of the Institute for Systems Biology (ISB) in Seattle, Washington. Dr. Hood’s research has focused on the study of molecular immunology, biotechnology, and genomics. Prior to his work at the ISB, Dr. Hood was the founder and Chairman of the cross-disciplinary Department of Molecular Biotechnology at the University of Washington. Dr. Hood began his professional career at Caltech where he and his colleagues pioneered four instruments — the DNA gene sequencer and synthesizer, and the protein synthesizer and sequencer — which comprise the technological foundation for contemporary molecular biology. Dr. Hood has also played a role in founding numerous biotechnology companies, including Amgen, Applied Biosystems, Systemix, Darwin and Rosetta. He has published more than 500 peer-reviewed papers, received 14 patents, and has co-authored textbooks in biochemistry, immunology, molecular biology, and genetics, and is a member of the National Academy of Sciences, the American Philosophical Society, the American Association of Arts and Sciences, and the Institute of Medicine.
Harvey F. Lodish, Ph.D.
Member, Whitehead Institute for Biomedical Research
Professor of Biology and Bioengineering, MIT
Dr. Lodish received his B.A. Summa Cum Laude and with Highest Honors in Chemistry and Mathematics, from Kenyon College, and his Ph.D. in genetics with Dr. Norton Zinder from the Rockefeller University. He continued post-doctoral work at the M.R.C. Laboratory of Molecular Biology with Dr. Sydney Brenner and Dr. Francis Crick. He currently serves as a Professor at MIT and the Whitehead Institute for Biomedical Research. Dr. Lodish has served on advisory panels for the NIH, NSF, and American Cancer Society, and on the advisory boards of several institutions, including the Biozentrum of the University of Basle, the European Molecular Biology Laboratory in Heidelberg, the Center for Molecular Biology Heidelberg (ZMBH) in Germany, and the PEW Scholars Program in Biomedical Sciences. He was chair of the advisory board of the Division of Basic Sciences of the Fred Hutchinson Cancer Center and of the Cleveland Clinic Lerner Research Institute and is currently Chair of the Scientific Advisory Board of Children’s Hospital, Boston. He is currently a member of the Board of Trustees of Kenyon College and of Children’s Hospital, Boston. He also serves on the Visiting Committee of the California Institute of Technology Division of Biology. Dr. Lodish is a member of the National Academy of Sciences. He was a founder and scientific advisory board member of Genzyme, Inc., Arris Pharmaceuticals, Inc., and Millennium Pharmaceuticals, Inc. He previously served on the Scientific Advisory Board of Astra and then AstraZeneca Pharmaceuticals and of the Eisai Research Institute.
Barry Sharpless, Ph.D.
W.M. Keck Professor of Chemistry, The Scripps Research Institute
Nobel Laureate, Chemistry, 2001
Dr. Sharpless received his B.S. from Dartmouth College and his Ph.D. from Stanford University. He completed post-doctoral studies with J.P. Collman at Stanford and with Konrad Bloch at Harvard. In 1970, Dr. Sharpless was appointed to the position of Assistant Professor at the Massachusetts Institute of Technology (MIT). At that time, he joined the faculty of the Scripps Research Institute (TSRI), where today he is the W. M. Keck Professor of Chemistry and a member of the Skaggs Institute for Chemical Biology. In 2001, Dr. Sharpless shared the Nobel Prize in Chemistry with William S. Knowles and Ryoji Noyori for their work on chemical synthesis reactions. His Nobel Prize citation says, “Many scientists have identified Sharpless’ epoxidation [discovered with Tsutomu Kastsuki in 1980] as the most important discovery in the field of synthesis during the past few decades.”
Today, Dr. Sharpless continues to pursue new methods for selectively controlling chemical reactions. A recent advance is “Click Chemistry” a set of powerful, selective reactions that enable the rapid synthesis of new compounds. Click chemistry is an integral part of research in Dr. Sharpless’ lab at TSRI and has provided a foundation for numerous collaborations with biologists at TSRI and at other leading research organizations.
David A. Tirrell, Ph.D.
Ross McCollum-William H. Corcoran Professor and Professor of Chemistry and Chemical Engineering
Chair, Division of Chemistry and Chemical Engineering, CalTech
Co-Founder, ALLOZYNE
Dr. Tirrell received his B.S. and Ph.D. degrees from MIT and the University of Massachusetts, respectively. Dr. Tirrell was an assistant professor in the Department of Chemistry at Carnegie-Mellon University, and then returned to the University of Massachusetts as the Director of the Materials Research Laboratory and Barrett Professor of Polymer Science and Engineering. Dr. Tirrell currently serves as Division Chair for Chemistry and Chemical Engineering at Caltech. He is a Fellow of the American Academy of Arts and Sciences and a member of the National Academy of Sciences. Dr. Tirrell was Editor of the Journal of Polymer Science, Part A: Polymer Chemistry, and has served on the editorial boards of Macromolecules, ChemBioChem, Accounts of Chemical Research, Chemical and Engineering News, and several other journals. Dr. Tirrell chaired the 1994 Gordon Research Conference on Polymers in Biosystems and the 1995 Gordon Conference on Chemistry of Supramolecules and Assemblies.